Hotel Republic San Diego, Autograph Collection

421 West B Street, Downtown San Diego, San Diego, United States - Gaslamp Quarter hub

Situated approximately 25 minutes' walk from San Diego History Center, the 4-star non-smoking Hotel Republic San Diego, Autograph Collection features a ballroom for planning various activities. Boasting a location in proximity to Little Italy, the hotel comprises 284 rooms and 2 restaurants.

Location

The modern hotel has a convenient setting 1.5 miles from San Diego Zoo, while natural sights like Chicano Park are 2.1 miles away. The circular San Diego Air & Space Museum is about a 10-minute drive from the luxury Republic San Diego, Autograph Collection, which is also situated in close proximity to American Plaza. Such entertainment attractions as House of Blues San Diego Live Music Venue are also 0.5 miles away. The accommodation is situated around a 5-minute stroll from Santa Fe Depot train station and a 5-minute drive from San Diego International airport.

Rooms

Tea and coffee making equipment along with a flat-screen TV with satellite channels are provided in each of the allergy-friendly rooms at Hotel Republic San Diego, Autograph Collection. Along with a separate toilet and a shower, bathroom comforts also include dressing gowns and a shower cap. These rooms offer views of the urban.

Food & Drinks

Onsite restaurants are represented by American-style and à la carte options, which will provide guests with a choice of American or local cuisines on their menus. The lounge bar provides you with a place to unwind. Animae is situated a stone's throw from the Republic San Diego, Autograph Collection.

Leisure & Activities

In order to stay active, guests can use yoga instruction, elliptical machines, and treadmills at the San Diego hotel. Guests staying at this property are welcome to join fitness classes at a fitness studio.

Why choose Hotel Republic San Diego, Autograph Collection

Select room
  • Contemporary accommodations with city views

  • Gourmet dining at two restaurants

  • 24-hour fitness center available

  • Veranda MClub for elite members

Main amenities

  • Free Wi-Fi

  • Parking

  • 24-hour services

  • Express check-in/ -out

  • Fitness/Gym

  • On-site Dining

  • Meeting facilities

  • Child-friendly

  • Wheelchair access

  • Air conditioning

  • Pets

General
  • Free Wi-Fi
  • Parking
  • 24-hour services
  • Express check-in/ -out
  • Fitness/Gym
  • On-site Dining
  • Meeting facilities
  • Child-friendly
  • Wheelchair access
  • Air conditioning
  • Pets
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Internet

  • Free Wi-Fi
  • Free Wi-Fi in rooms

Parking options

  • Parking
  • Valet parking

Activities

  • Fitness centre
  • Yoga class

Property services

  • Safe deposit box
  • 24-hour reception
  • Express check-in/ -out
  • Security
  • Luggage storage
  • Pet amenities available
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Welcome drink
  • Happy hour

Dining options

  • Restaurant
  • Bar/ Lounge area

Business facilities

  • Meeting/ Banquet facilities
  • Fax/Photocopying

For kids

  • Cots
  • Children's menu

Recreation

  • Live entertainment
  • Leisure/ TV room

For disabled guests

  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Toilet for disabled
  • Bathroom for disabled

In the rooms

  • Air conditioning
  • Heating
  • Sitting area
  • Terrace
  • Garden furniture
  • Tea and coffee facilities
  • Ironing facilities

In the bathroom

  • Free toiletries

Devices

  • Flat-screen TV
  • AM/FM alarm clock

Design

  • Carpeted floor

General facilities

  • No smoking on site
  • Allergy-free rooms
  • Lift
  • ATM/Cash machine
  • Smoke detectors
  • Electric vehicle charging station
  • Fire extinguishers
  • Key card access

Pets

  • Pets allowed

Important information

Check-in:
from 16:00 until 23:59
Check-out:
until 11:00
  • Children and extra beds
  • There are no extra beds provided in a room.
  • There are no cribs provided in a room.

Enter dates to see availability

From USD 126 per night
Check-in 12 Feb 2026
Check-out 13 Feb 2026
Guests 2 guests

Adults:

2

Children:

0

Rooms

Photos of Hotel Republic San Diego, Autograph Collection

Location of Hotel Republic San Diego, Autograph Collection

421 West B Street, Downtown San Diego, San Diego, United States

 -  Gaslamp Quarter hub
Attractions
Great restaurants
Transportation

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    100% Verified Reviews
    Enter dates to see availability
    From USD 126 per night
    Check-in 12 Feb 2026
    Check-out 13 Feb 2026
    Guests 2 guests

    Adults:

    2

    Children:

    0
    Check-in & out
    12 Feb 2026
    13 Feb 2026
    Guests
    2 guests
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    Details:

    421 West B Street, San Diego, United States

    Important information
    Hotel Republic San Diego, Autograph Collection
    Check-in:
    from 16:00 until 23:59
    Check-out:
    until 11:00
    • Children and extra beds
    • There are no extra beds provided in a room.
    • There are no cribs provided in a room.